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Stem Cell Related Patent Number US5733542
| Title: | Enhancing bone marrow engraftment using MSCS | | Inventors: | Haynesworth, Stephen E.; Cleveland Heights, OH, USA
Caplan, Arnold I.; Cleveland Heights, OH, USA
Gerson, Stanton L.; Pepper Pike, OH, USA
Lazarus, Hillard M.; Shaker Heights, OH, USA | | Summary: | Described herein is a method of enhancing bone marrow engraftment by the administration of mesenchymal stem cells. The invention relates to a system for culturally expanding and administering a mesenchymal stem cell preparation in an amount effective to promote bone marrow engraftment. Further provided are methods for isolating homogeneous mesenchymal stem cells, and therapeutic applications of such cells in the acceleration of blood and marrow cell regeneration. | | Abstract: | Method and preparations for enhancing bone marrow engraftment in an individual by administering (i) a culturally expanded mesenchymal stem cell preparation and (ii) a bone marrow graft. The mesenchymal stem cells are administered in an mount effective to promote engraftment of the bone marrow. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US5733542 | | Application Number: | US1995000377771 | | Date Filed: | 24/01/1995 | | Date Published: | 31/03/1998 | | Assignee: | None |
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