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Stem Cell Related Patent Number US5817773
| Title: | Stimulation, production, culturing and transplantation of stem cells by fibroblast growth factors | | Inventors: | Wilson, Elaine Lynette; New York, NY, USA
Gabrilove, Janice; New York, NY, USA | | Summary: | Described herein is a method for increasing the concentration of hematopoietic progenitor cells. The invention relates to precursors of mature blood or lymph cells and methods of stimulating their proliferation in vivo by the administration of a fibroblast growth factor. Further disclosed are associated culturing conditions, engraftment techniques, and methods by which such growth factors may be utilized to stimulate the proliferation of hematopoietic cells and their progeny whether in vitro, in situ or in vivo. Therapeutic applications are included for the treatment of diseases associated with dysplasia or aplasia of a bone marrow cell lineage. | | Abstract: | Fibroblast growth factors are used in vivo, in situ and in vitro to stimulate stem cells, hemopoiesis, the immune system, transplant donor cells, culture and/or engraftment, wherein the use of fibroblast growth factors is disclosed for the stimulation of stem cells or hemopoietic cells, supporting cells and their progeny, in vitro, in situ and in vivo, as well as corresponding engrafting sites in vivo. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US5817773 | | Application Number: | US1996000605919 | | Date Filed: | 23/02/1996 | | Date Published: | 06/10/1998 | | Assignee: | New York University, New York, NY, USA
Sloan-Kettering Institute for Cancer Research, New York, NY, USA |
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