|
|
|
Stem Cell Related Patent Number US6096540
| Title: | Differentiation of granulocytic and monocytic progenitor cells | | Inventors: | Olweus, Johanna; Palo Alto, CA, USA
Lund-Johansen, Fridtjof; Palo Alto, CA, USA
Thompson, Peter; Danville, CA, USA | | Summary: | Described herein are methods of distinguishing monocytic and granulocytic pre-cursors from CD34-positive cells via a process of measuring the level of expression of macrophage-colony stimulating factor receptor and isolated precursor cells. The invention relates to a method of distinguishing progenitors committed to the granulo-monocytic lineage in a population containing CD34+ cells, by contacting the cells with antibodies specific for CD34, M-CSFR and CD64, which is followed by a process of detection via flow cytometry by which the cells that are CD34hi M-CSFR+ CD64- are identified and from which a CD34hi M-CSFR+ CD64- phenotype indicates granulo-monocytic lineage progenitor cells. | | Abstract: | | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6096540 | | Application Number: | US1996000724725 | | Date Filed: | 30/09/1996 | | Date Published: | 01/08/2000 | | Assignee: | Becton Dickinson and Company, Franklin Lakes, NJ, USA |
|
|
