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Stem Cell Related Patent Number US6500943
| Title: | Promoter | | Inventors: | Mano, Hiroyuki; Utsunomiya, Japan
Sakata, Tsuneaki; Toyonaka, Japan
Hasegawa, Mamoru; Tsukuba, Japan
Tabata, Toshiaki; Tsukuba, Japan | | Summary: | This invention introduces DNA with a Tec tyrosine kinase promoter activity for the expression of foreign genes in hematopoietic stem cells and liver cells. Described herein are methods of providing a DNA with promoter activity of Tec tyrosine kinase and a vector having incorporated within it the promoter which thereby enables a high level expression of an exogenous gene in hematopoietic stem cells and hepatic cells. Precise nucleotide sequences are disclosed, as are therapeutic applications in the treatment of liver disease. | | Abstract: | The present invention provides a DNA having promoter activity of Tec tyrosine kinase and a vector having incorporated within it the promoter to thereby enable a high level expression of an exogenous gene in hematopoietic stem cells and hepatic cells. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6500943 | | Application Number: | US2001000045428 | | Date Filed: | 08/11/2001 | | Date Published: | 31/12/2002 | | Assignee: | Dnavec Research Inc., Ibaraki, Japan |
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