|
|
|
Stem Cell Related Patent Number US6867006
| Title: | Antibodies to human chemotactic protein | | Inventors: | Li, Haodong; Gaithersburg, MD, USA
Ruben, Steven M.; Olney, MD, USA
Sutton, III, Granger; Columbia, MD, USA | | Summary: | Described herein is a new polynucleotide encoding a human chemotactic polypeptide, the associated DNA and RNA, and a procedure for producing such a polypeptide by recombinant techniques. Further disclosed are polypeptide antagonists and diagnostic assays for identifying mutations in nucleic acid sequences encoding such a polypeptide, and for detecting altered levels of the polypeptide in the screening and detection of diseases. Applications are included in stem cell mobilization, myeloprotection, neuronal protection, wound healing, in the treatment of cancer and parasitic infections, and in the regulation of hematopoiesis. | | Abstract: | A human chemotactic polypeptide, DNA (RNA) encoding it, and a procedure for producing such a polypeptide by recombinant techniques are disclosed. Also disclosed are methods of using the polypeptide for a number of purposes, including: stem cell mobilization, myeloprotection, neuronal protection, treating tumors, wound healing, treating parasitic infection, and regulating hematopoiesis. Also disclosed are polypeptide antagonists and diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases are also disclosed. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6867006 | | Application Number: | US2002000141965 | | Date Filed: | 10/05/2002 | | Date Published: | 15/03/2005 | | Assignee: | Human Genome Sciences, Inc., Rockville, MD, USA |
|
|
