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Stem Cell Related Patent Number US7041282
| Title: | Ligands for flt3 receptors | | Inventors: | Lyman, Stewart D.; Seattle, WA, USA
Beckmann, M. Patricia; Poulsbo, WA, USA | | Summary: | Described herein are isolated ligands for flt3-L receptors capable of transducing self-renewal signals to regulate the growth, proliferation or differentiation of progenitor cells and stem cells. The invention is related to flt3-L as an isolated protein, the DNA encoding the flt3-L, host cells transfected with cDNAs encoding flt3-L, compositions comprising flt3-L, methods of improving gene transfer to a mammal using flt3-L, and methods of improving transplantations using fit3-L. Therapeutic applications of flt3-L are provided, such as in the treatment of patients with anemia, AIDS and various types of cancer. | | Abstract: | Ligands for flt3 receptors capable of transducing self-renewal signals to regulate the growth, proliferation or differentiation of progenitor cells and stem cells are disclosed. The invention is directed to flt3-L as an isolated protein, the DNA encoding the flt3-L, host cells transfected with cDNAs encoding flt3-L, compositions comprising flt3-L, methods of improving gene transfer to a mammal using flt3-L, and methods of improving transplantations using fit3-L. Flt3-L finds use in treating patients with anemia, AIDS and various cancers. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US7041282 | | Application Number: | US2001000983806 | | Date Filed: | 25/10/2001 | | Date Published: | 09/05/2006 | | Assignee: | Immunex Corporation, Seattle, WA, USA |
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